No cat breed is truly allergen-free. The main cat allergen, Fel d 1, is made in a cat’s saliva and spread over the coat during grooming, and research shows it varies far more between individual cats than by appearance. Studies on dogs found no evidence that “hypoallergenic” breeds release less allergen into homes. That said, some individual cats produce consistently low levels, and there are proven ways to live more comfortably with a cat.
This guide explains what makes cats allergenic, what research says about breeds and low-allergen cats, newer approaches like allergen-reducing cat food, and practical steps for allergic cat lovers. For more, see our pet allergy guides.
Jump to: Quick answer · What causes cat allergy · Do breeds matter? · Newer approaches · Before you adopt · Living with a cat · FAQ
Quick answer
- Fel d 1 is the main allergen: up to 90% of cat-allergic adults react to it.
- Individual cats vary widely: in a year-long study of 64 house cats, average saliva Fel d 1 ranged from 0.4 to 35 micrograms per milliliter.
- Looks don’t predict it: sex, coat color and body size weren’t linked to Fel d 1 levels; older cats tended to have less.
- “Hypoallergenic” dog breeds didn’t lead to lower allergen levels in homes in a Dutch study, and allergists call the idea a myth for dogs and cats.
- What helps: keep cats out of the bedroom, use HEPA filtration, clean often, and ask an allergist about treatment, including allergy shots.
What causes cat allergy
Fel d 1 is the major cat allergen, causing allergic (IgE) reactions in up to 90% of cat-allergic adults. Cats secrete it in saliva and spread it to their fur when they groom. From there it ends up in dander, on furniture and in household dust.
Because the allergen is carried on small particles that stay in the air longer, the EPA notes that a significant fraction of cat and dog allergen can be removed by air filters, unlike heavier allergens such as dust mite debris. See air purifier myths.
Do “hypoallergenic” breeds work?
| Study | What was studied | Findings |
|---|---|---|
| Bastien et al., 2019, cats | Saliva Fel d 1 in 64 domestic shorthair cats, sampled for a year | Wide, continuous range between cats (0.4 to 35 µg/ml); not linked to sex, coat color or size; older cats lower; some cats had stable low levels identifiable with a few saliva tests |
| Vredegoor et al., 2012, dogs | Dog allergen (Can f 1) in hair and homes of “hypoallergenic” breeds (Labradoodle, Poodle, Spanish Waterdog, Airedale) vs other dogs | “Hypoallergenic” dogs had higher allergen in hair samples; no difference in airborne levels; no evidence to call any breed hypoallergenic |
For cats, breeds such as Siberian, Balinese and Rex cats are often marketed as better for allergies. We couldn’t find strong, independent evidence that any cat breed reliably produces less allergen. The cat study above suggests that the individual cat matters more than the breed.
Note: the cat saliva study was conducted by researchers employed by a pet food company.
Newer approaches
One newer approach targets Fel d 1 after the cat makes it. In a 2019 trial by the same company’s researchers, cats fed a diet containing egg-derived antibodies against Fel d 1 had lower active Fel d 1 in their saliva within 3 weeks: 82% of treated cats showed a drop of at least 20% from baseline, compared with 38% of control cats. The authors said more research is needed, and the study measured allergen in cat saliva, not symptoms in allergic people.
Before you adopt
- Get tested. An allergist can confirm whether you’re allergic to cats and how strongly.
- Spend time with the specific cat you’re considering, more than once, before committing.
- Don’t rely on breed labels. Individual cats vary more than breeds.
- Plan your home setup before the cat arrives: bedroom off-limits, HEPA filtration, easy-to-clean floors.
Living with a cat when you’re allergic
- Keep the cat out of the bedroom so you’re not exposed while you sleep, as ACAAI advises for pet allergy.
- Use a HEPA air purifier sized for the room, and a HEPA vacuum. See choosing a vacuum for allergies.
- Wash bedding and throws often in hot water.
- Wash your hands after petting the cat.
- Ask about allergy shots: Mayo Clinic lists pet dander among the indoor allergens shots can treat. See allergy drops vs shots.
Hosting guests who are allergic to your cat? See preparing for pet-allergic guests.
This guide is general information, not medical advice. Read our medical disclaimer.
Frequently asked questions
Are there hypoallergenic cats?
Not truly. All cats make Fel d 1. Some individual cats produce consistently low levels, but breed or appearance doesn’t reliably predict it.
What makes people allergic to cats?
Mainly Fel d 1, a protein in cat saliva that spreads to the fur during grooming and ends up in dander and dust. Up to 90% of cat-allergic adults react to it.
Are Siberian cats hypoallergenic?
They’re often marketed that way, but we couldn’t find strong independent evidence. Spend time with the specific cat before adopting.
Does cat food that reduces allergens work?
A company-funded trial found a diet with anti-Fel d 1 egg antibodies lowered active Fel d 1 in cat saliva within 3 weeks. Effects on people’s symptoms need more study.
How can I live with a cat if I’m allergic?
Keep the cat out of your bedroom, use HEPA filtration, clean often, wash hands after petting, and talk to an allergist about treatment.
Sources
- Bastien BC, Gardner C, Satyaraj E. Influence of time and phenotype on salivary Fel d1 in domestic shorthair cats. J Feline Med Surg. 2019;21(10):867-874.
- Satyaraj E, Li Q, Sun P, Sherrill S. Anti-Fel d1 immunoglobulin Y antibody-containing egg ingredient lowers allergen levels in cat saliva. J Feline Med Surg. 2019;21(10):875-881.
- Vredegoor DW, Willemse T, Chapman MD, et al. Can f 1 levels in hair and homes of different dog breeds: lack of evidence to describe any dog breed as hypoallergenic. J Allergy Clin Immunol. 2012;130(4):904-909.
- Lockey RF. The myth of hypoallergenic dogs (and cats). J Allergy Clin Immunol. 2012;130(4):910-911.
- U.S. Environmental Protection Agency. Residential air cleaners: a technical summary. 2018.
- American College of Allergy, Asthma and Immunology. Hay fever (rhinitis).
Last reviewed: October 21, 2026.







